Key Resources Table

Please use the form below to complete the Key Resources Table (KRT) for the STAR Methods section of your paper. While completing the form, you may save your work at any time. Clicking “Save” at the bottom of the form generates a Submission ID, which is sent with a shareable link to the e-mail address entered below. This ID and link can be used by you or your co-authors to access and complete the in-progress form. After clicking "Submit", you will have the opportunity to download and edit the KRT as a Word document, and a copy will also be e-mailed to you. Please submit the KRT document along with your manuscript files. If you prefer to create the KRT manually using a Word template, please download the template here.

The KRT highlights the genetically modified organisms and strains, cell lines, reagents, software, and source data essential to reproduce results presented in the manuscript. Depending on the nature of the study, this may include standard laboratory materials (i.e., food chow for metabolism studies), but the KRT is not meant to be a comprehensive list of all materials and resources used (e.g., essential chemicals such as SDS, sucrose, or standard culture media don't need to be listed in the KRT).

Before completing the form, please review these guidelines:

General

  • Items in the KRT must also be reported in the Method Details section of the STAR Methods text.

  • Please note that ALL references cited in the KRT must be included in the manuscript's References list.

Reagent or Resource

  • Provide the full descriptive names of items so that they can be identified and linked with their description in the manuscript (e.g., provide version number for software, host source for antibody, strain name, etc.).

Source

  • Report the company, manufacturer, or individual that provided the item or where the item can be obtained (e.g., stock center or repository).

  • For materials distributed by Addgene, please cite the article describing the plasmid and include "Addgene" as part of the Identifier.

  • If an item is from another lab, please include the name of the principal investigator and a citation if it has been previously published.

  • If the material is being reported for the first time in the current paper, please indicate as "This Paper".

Identifier

  • Include catalog numbers (entered in the column as "Cat#" followed by the number, e.g., Cat#3879S).

  • Where available, please include unique entities such as RRIDs, Model Organism Database numbers, accession numbers, and PDB or CAS IDs. For software or data resources, please include the URL where the resource can be downloaded. Please see the Elsevier list of Data Repositories with automated bidirectional linking for details.

  • When listing more than one identifier for the same item, use semicolons to separate them (e.g., Cat#3879S; RRID: AB_2255011).

  • If an identifier is not available, please enter "N/A" in the column.

  • A note about RRIDs: Elsevier highly recommends using RRIDs as the identifier (in particular for antibodies and organisms, but also for software tools and databases). For more details on how to obtain or generate an RRID for existing or newly generated resources, please visit the RII or search for RRIDs.



1. Did this study use antibodies?
If applicable and available, please include the lot number or clone identity in the Identifier column, in addition to the catalog number and/or RRID.

REAGENT or RESOURCE? SOURCE? IDENTIFIER?
Add Remove
more items

2. Did this study use bacterial and virus strains?

REAGENT or RESOURCE? SOURCE? IDENTIFIER?
Add Remove
more items

3. Did this study use biological samples?
Please include all samples obtained from commercial sources or biological repositories.

REAGENT or RESOURCE? SOURCE? IDENTIFIER?
Add Remove
more items

4. Did this study use chemicals, peptides, or recombinant proteins?

REAGENT or RESOURCE? SOURCE? IDENTIFIER?
Add Remove
more items

5. Did this study use critical commercial assays?

REAGENT or RESOURCE? SOURCE? IDENTIFIER?
Add Remove
more items

6. Did you deposit data or use data published in another paper or available from a repository in this study?

REAGENT or RESOURCE? SOURCE? IDENTIFIER?
Add Remove
more items

7. Did this study use experimental models: cell lines?

REAGENT or RESOURCE? SOURCE? IDENTIFIER?
Add Remove
more items

8. Did this study use experimental models: organisms and strains?
In the Reagent or Resource column, please include all models used in the paper and describe each strain as: “model organism: name used for strain in paper: genotype” (e.g., “Mouse: OXTRfl/fl: B6.129(SJL)-Oxtrtm1.1Wsy/J”).

REAGENT or RESOURCE? SOURCE? IDENTIFIER?
Add Remove
more items

9. Did this study use oligonucleotides?
The number of primers and RNA sequences that may be listed is restricted to ten. If there are more than ten primers or RNA sequences to report, please provide this information as a supplemental table and reference this file (e.g., See Table S1 for XX) in the Source column.

REAGENT or RESOURCE? SOURCE? IDENTIFIER?
Add Remove
more items

10. Did this study use recombinant DNA?

REAGENT or RESOURCE? SOURCE? IDENTIFIER?
Add Remove
more items

11. Did this study use software and algorithms?
Please note that newly generated software code mentioned in the Methods Details or Data and Software Availability section needs to be also included in the Software and Algorithms section of the KRT. For previously available software critical for experiments and analysis, in the Source column, please provide the company name if it is commercially available or cite the paper in which it has been initially described.

REAGENT or RESOURCE? SOURCE? IDENTIFIER?
Add Remove
more items

12. Did this study contain additional information not listed above that you consider to be relevant for this table?

REAGENT or RESOURCE? SOURCE? IDENTIFIER?
Add Remove
more items